Oteseconazole
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole... more
Product information "Oteseconazole"
Description: Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM). Target: P450, Antifungal. Smiles: O[C@@](Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(cn1)-c1ccc(OCC(F)(F)F)cc1. References: Warrilow AG, et al. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme. Antimicrob Agents Chemother. 2014 Dec,58(12):7121-7.
| Keywords: | VT-1161 |
| Supplier: | TargetMol |
| Supplier-Nr: | T16412 |
Properties
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| MW: | 527.39 D |
| Formula: | C23H16F7N5O2 |
Database Information
| CAS : | 1340593-59-0| Matching products |
| KEGG ID : | K05917 | Matching products |
| Protein Atlas Nr. : | Metabolism |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H228, H315, H319 |
| P Phrases: | P210, P240, P241, P264, P280, P321, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362+P364, P370+P378 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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