OSI-027

Item number	Size	Delivery time	Price
TGM-T6319-1mg	1 mg	7 - 10 business days*	37.00€
TGM-T6319-2mg	2 mg	7 - 10 business days*	48.00€
TGM-T6319-5mg	5 mg	7 - 10 business days*	77.00€
TGM-T6319-1mL	1 ml	7 - 10 business days*	81.00€
TGM-T6319-10mg	10 mg	7 - 10 business days*	140.00€
TGM-T6319-25mg	25 mg	7 - 10 business days*	259.00€
TGM-T6319-50mg	50 mg	7 - 10 business days*	408.00€
TGM-T6319-100mg	100 mg	7 - 10 business days*	596.00€

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Description: OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with... more

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Product information "OSI-027"

Description: OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kalpha, PI3Kbeta, PI3Kgamma or DNA-PK. Phase 1. Target: Autophagy, PI3K, mTOR, DNA-PK. Smiles: COc1cccc2=C\C(N=c12)=c1/nc(C2CCC(CC2)C(O)=O)n2NC=NC(N)=c12. References: Falcon BL, et al. Cancer Res, 2011, 71(5), 1573-1583.

Keywords:	OSI027, ASP4786
Supplier:	TargetMol
Supplier-Nr:	T6319

Properties

Application:	mTORC1 / mTORC2 inhibitor
MW:	406.44 D
Formula:	C21H22N6O3

Database Information

CAS :	936890-98-1\| Matching products
KEGG ID :	K07203 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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