Obatoclax Mesylate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 µM) and can induce... more
Product information "Obatoclax Mesylate"
Description: Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 µM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. Target: Autophagy, Parasite, BCL. Smiles: CS(O)(=O)=O.COc1cc([nH]c1=Cc1[nH]c(C)cc1C)=C1C=c2ccccc2=N1. References: Nguyen M, et al. Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis. Proc Natl Acad Sci U S A. 2007 Dec 4,104(49):19512-7. Epub 2007 Nov 26.
| Keywords: | GX15-070, Obatoclax |
| Supplier: | TargetMol |
| Supplier-Nr: | T6275 |
Properties
| Application: | Targets apoptosis regulator Bcl-2 (BCL2) |
| MW: | 413.49 D |
| Formula: | C20H19N3O·CH4O3S |
Database Information
| CAS : | 803712-79-0| Matching products |
| KEGG ID : | K02161 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H315 |
| P Phrases: | P264, P270, P280, P321, P330, P301+P310, P302+P352, P332+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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