O-desethyl Dapagliflozin

O-desethyl Dapagliflozin is an inhibitor of sodium-glucose cotransporter 2 (SGLT2, IC50 = 9.4 nM) and active metabolite of dapagliflozin (Cay-11574). It is selective for SGLT2 over SGLT1 (IC50 = 970 nM).Formal Name: (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-D-glucitol. CAS Number: 864070-37-1. Molecular Formula: C19H21ClO6. Formula Weight: 380.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: O[C@H]([C@H]1O)[C@H](C(C=C2)=CC(CC(C=C3)=CC=C3O)=C2Cl)O[C@@H]([C@H]1O)CO. InChi Code: InChI=1S/C19H21ClO6/c20-14-6-3-11(8-12(14)7-10-1-4-13(22)5-2-10)19-18(25)17(24)16(23)15(9-21)26-19/h1-6,8,15-19,21-25H,7,9H2/t15-,16-,17+,18-,19+/m1/s1. InChi Key: ODQAIMBPQWETBE-FQBWVUSXSA-N.