NU6140

Item number	Size	Manual	Delivery time	Price
TGM-T16359-1mg	1 mg	-	7 - 10 business days*	41.00€
TGM-T16359-2mg	2 mg		7 - 10 business days*	57.00€
TGM-T16359-5mg	5 mg		7 - 10 business days*	95.00€
TGM-T16359-1mL	1 ml		7 - 10 business days*	106.00€
TGM-T16359-10mg	10 mg		7 - 10 business days*	159.00€
TGM-T16359-25mg	25 mg		7 - 10 business days*	321.00€
TGM-T16359-50mg	50 mg		7 - 10 business days*	517.00€
TGM-T16359-100mg	100 mg		7 - 10 business days*	753.00€
TGM-T16359-500mg	500 mg	-	7 - 10 business days*	1,550.00€

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Description: NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 µM). It shows 10- to... more

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Product information "NU6140"

Description: NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 µM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and has anti-cancer activity. Target: CDK, Aurora Kinase. Smiles: CCN(CC)C(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1. References: Pennati M, et al. Potentiation of apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation. Mol Cancer Ther. 2005 Sep,4(9):1328-37.

Supplier:	TargetMol
Supplier-Nr:	T16359

Properties

Application:	Cdk2 inhibitor
MW:	422.52 D
Formula:	C23H30N6O2

Database Information

CAS :	444723-13-1\| Matching products
KEGG ID :	K02206 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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