NSC 44625

NSC 44625 is an inhibitor of carbonic anhydrase II (CAII, Ki = 63 nM for the human enzyme). It is selective for CAII over CAI (Ki = 5,800 nM for the human enzyme) but also inhibits beta-carbonic anhydrase (Ki = 223 nM for the S. cerevisiae enzyme).Formal Name: 4-amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide. CAS Number: 654-62-6. Synonyms: Bendroflumethiazide Impurity A, 2,4-Disulfamyl-5-trifluoromethylaniline. Molecular Formula: C7H8F3N3O4S2. Formula Weight: 319.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble: >10 mg/ml, Ethanol: Sparingly Soluble: 1-10 mg/ml. SMILES: O=S(N)(C1=C(N)C=C(C(F)(F)F)C(S(=O)(N)=O)=C1)=O. InChi Code: InChI=1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17). InChi Key: KRVABEGPNKGLOT-UHFFFAOYSA-N.