NS 1643
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
NS 1643 is an activator of the human ether-a-go-go related gene (ERG1, KCNH2, hERG) KV11.1... more
Product information "NS 1643"
NS 1643 is an activator of the human ether-a-go-go related gene (ERG1, KCNH2, hERG) KV11.1 channel (EC50 = 10.5 µM). It also activates the KV11.2 (ERG2, KCNH6) channel, but evokes a distinctly different response from that of KV11.1. NS 1643 is commonly used in cells or isolated tissues.Formal Name: N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]-urea. CAS Number: 448895-37-2. Molecular Formula: C15H10F6N2O3. Formula Weight: 380.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml, Ethanol: 10 mg/ml. lambdamax: 211, 240, 261, 292 nm. SMILES: OC1=C(C=C(C=C1)C(F)(F)F)NC(NC2=CC(C(F)(F)F)=CC=C2O)=O. InChi Code: InChI=1S/C15H10F6N2O3/c16-14(17,18)7-1-3-11(24)9(5-7)22-13(26)23-10-6-8(15(19,20)21)2-4-12(10)25/h1-6,24-25H,(H2,22,23,26). InChi Key: NJFVQMRYJZHGME-UHFFFAOYSA-N.
| Keywords: | N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]-urea |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 20343 |
Properties
| Application: | KCNH2 activator |
| MW: | 380.2 D |
| Formula: | C15H10F6N2O3 |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 448895-37-2| Matching products |
| KEGG ID : | K04905 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H319 |
| P Phrases: | P264, P270, P280, P321, P330, P301+P310, P305+P351+P338, P337+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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