(-)-Norepinephrine (bitartrate hydrate)

(-)-Norepinephrine is the endogenous isomer of (±)-norepinephrine (Cay-35580) that acts as a neurotransmitter and hormone and is biosynthesized from dopamine by dopamine beta-hydroxylase. It is an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for alpha1, alpha2, and beta1 adrenoceptors, respectively). Through these receptors, (-)-norepinephrine regulates diverse processes, including those in neurological, immunological, and vascular systems. Formulations containing (-)-norepinephrine have been used for the restoration of blood pressure in acute hypotensive states.Formal Name: 4-[(1R)-2-amino-1-hydroxyethyl]-1,2-benzenediol (2R,3R)-2,3-dihydroxybutanedioate, monohydrate. CAS Number: 108341-18-0. Synonyms: Arterenol, Levarterenol, NE, L-Noradrenaline. Molecular Formula: C8H11NO3 . C4H6O6 . H2O. Formula Weight: 337.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 224, 283 nm. SMILES: OC1=C(O)C=CC([C@@H](O)CN)=C1.OC([C@H](O)[C@@H](O)C(O)=O)=O.O. InChi Code: InChI=1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5,5-1(3(7)8)2(6)4(9)10,/h1-3,8,10-12H,4,9H2,1-2,5-6H,(H,7,8)(H,9,10),1H2/t8-,1-,2-,/m01./s1. InChi Key: LNBCGLZYLJMGKP-LUDZCAPTSA-N.