NK 252

NK 252
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay19131-1 1 mg -

6 - 10 business days*

44.00€
Cay19131-5 5 mg -

6 - 10 business days*

117.00€
Cay19131-10 10 mg -

6 - 10 business days*

209.00€
Cay19131-25 25 mg -

6 - 10 business days*

469.00€
 
NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding... more
Product information "NK 252"
NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding site of Keap1. At 1.36 µM, it is reported to activate the NQO1-antioxidant response element in a luciferase reporter gene assay two-fold above background. NK 252 has been shown to downregulate the expression of fibrogenic genes, producing antifibrotic effects in a rat model of non-alcoholic steatohepatitis.Formal Name: N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)-urea. CAS Number: 1414963-82-8. Molecular Formula: C13H11N5O3. Formula Weight: 285.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 14 mg/ml. lambdamax: 275 nm. SMILES: O=C(NC1=NN=C(C2=CC=CO2)O1)NCC3=CC=CC=N3. InChi Code: InChI=1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19). InChi Key: FNSCFQXZZNCDAI-UHFFFAOYSA-N.
Keywords: N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)-urea
Supplier: Cayman Chemical
Supplier-Nr: 19131

Properties

Application: Nrf2 activator
MW: 285.3 D
Formula: C13H11N5O3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 1414963-82-8| Matching products
KEGG ID : K05638 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302
P Phrases: P264, P270, P301+310, P330, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "NK 252"
Write a review
or to review a product.
Viewed