Nitrocefin

The generation of beta-lactamases by bacteria affords resistance to several classes of beta-lactam antibiotics, including penicillins and cephalosporins. Nitrocefin is a chromogenic cephalosporin substrate commonly used to detect beta-lactamases in bacteria. The presence of beta-lactamase activity is indicated by the appearance of a red color that is proportional in intensity to the original concentration of nitrocefin.Formal Name: (6R)-3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7R-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS Number: 41906-86-9. Synonyms: Nitrocephin. Molecular Formula: C21H16N4O8S2. Formula Weight: 516.5. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml. lambdamax: 231, 286, 379 nm. SMILES: O=C(O)C1=C(CS[C@@]([C@@H]2NC(CC3=CC=CS3)=O)([H])N1C2=O)/C=C/C4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O. InChi Code: InChI=1S/C21H16N4O8S2/c26-16(9-14-2-1-7-34-14)22-17-19(27)23-18(21(28)29)12(10-35-20(17)23)4-3-11-5-6-13(24(30)31)8-15(11)25(32)33/h1-8,17,20H,9-10H2,(H,22,26)(H,28,29)/b4-3+/t17-,20-/m1/s1. InChi Key: LHNIIDJCEODSHA-OQRUQETBSA-N.