Nimbolide
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-kappaB,... more
Product information "Nimbolide"
Description: Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-kappaB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-kappaB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L). Target: Apoptosis, CDK, NF-kappaB. Smiles: C[C@]12[C@]3([C@]([C@@]4([C@](C)([C@@H]1CC(OC)=O)C=5[C@](O4)(C[C@H](C5C)C=6C=COC6)[H])[H])(OC(=O)[C@]3(C)C=CC2=O)[H])[H]. References: Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug,28(5):1026-35.
| Supplier: | TargetMol |
| Supplier-Nr: | T16324 |
Properties
| MW: | 466.52 D |
| Formula: | C27H30O7 |
Database Information
| CAS : | 25990-37-8| Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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