Nicorandil
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels,... more
Product information "Nicorandil"
Description: Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly by donating nitric oxide to activate the enzyme guanylate cyclase. Guanylate cyclase causes activation of cGMP leading to both arterial and venous vasodilatation by de-phosphorylation of the myosin light chain. Target: Potassium Channel. Smiles: [O-][N+](=O)OCCNC(=O)C1=CN=CC=C1. References: Sato T, et al. J Am Coll Cardiol, 2000, 35(2), 514-518.
| Keywords: | SG-75 |
| Supplier: | TargetMol |
| Supplier-Nr: | T0075 |
Properties
| MW: | 211.17 D |
| Formula: | C8H9N3O4 |
Database Information
| CAS : | 65141-46-0| Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H318 |
| P Phrases: | P264, P270, P280, P301+310, P305+351+338, P310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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