Netupitant N-oxide

Netupitant N-oxide is a metabolite of the neurokinin-1 (NK1) receptor antagonist netupitant (Cay-23809). Netupitant N-oxide is formed from netupitant by the cytochrome P450 (CYP) isoform CYP3A4.Formal Name: N,alpha,alpha-trimethyl-N-[6-(4-methyl-4-oxido-1-piperazinyl)-4-(2-methylphenyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide. CAS Number: 910808-11-6. Molecular Formula: C30H32F6N4O2. Formula Weight: 594.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly, heated, Methanol: slightly soluble. SMILES: O=C(C(C)(C)C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N(C)C2=CN=C(N3CCN(C)(CC3)=O)C=C2C4=C(C)C=CC=C4. InChi Code: InChI=1S/C30H32F6N4O2/c1-19-8-6-7-9-23(19)24-17-26(39-10-12-40(5,42)13-11-39)37-18-25(24)38(4)27(41)28(2,3)20-14-21(29(31,32)33)16-22(15-20)30(34,35)36/h6-9,14-18H,10-13H2,1-5H3. InChi Key: FKUOVQVMCOPBJS-UHFFFAOYSA-N.