Necrostatin-5
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis... more
Product information "Necrostatin-5"
Description: Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-alpha, with an EC50 of 240 nM. Target: Necroptosis, RIP kinase. Smiles: O=C1C=2C3=C(SC2N=C(SCC#N)N1C4=CC=C(OC)C=C4)CCCC3. References: González-Juarbe N, Gilley RP, Hinojosa CA, et al. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog. 2015,11(12):e1005337.
| Keywords: | Nec-5 |
| Supplier: | TargetMol |
| Supplier-Nr: | T37558 |
Properties
| Application: | Necroptosis inhibitor |
| MW: | 383.49 D |
| Formula: | C19H17N3O2S2 |
Database Information
| CAS : | 337349-54-9| Matching products |
| KEGG ID : | K02861 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H319, H413 |
| P Phrases: | P264, P273, P280, P305+351+338, P337+313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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