ND-646

Item number	Size	Delivery time	Price
TGM-TQ0243-1mg	1 mg	7 - 10 business days*	77.00€
TGM-TQ0243-5mg	5 mg	7 - 10 business days*	195.00€
TGM-TQ0243-1mL	1 ml	7 - 10 business days*	245.00€
TGM-TQ0243-10mg	10 mg	7 - 10 business days*	320.00€
TGM-TQ0243-25mg	25 mg	7 - 10 business days*	544.00€
TGM-TQ0243-50mg	50 mg	7 - 10 business days*	787.00€
TGM-TQ0243-100mg	100 mg	7 - 10 business days*	1,080.00€

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Description: ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1... more

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Product information "ND-646"

Description: ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2, with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. Target: Acetyl-CoA Carboxylase. Smiles: COc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(N)=O)-c1ncco1)OC1CCOCC1. References: Svensson RU, et al. Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models. Nat Med. 2016 Oct,22(10):1108-1119.

Supplier:	TargetMol
Supplier-Nr:	TQ0243

Properties

Application:	Acetyl-CoA carboxylase inhibitor
MW:	568.64 D
Formula:	C28H32N4O7S

Database Information

CAS :	1434639-57-2\| Matching products
KEGG ID :	K11262 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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