N1-Acetylspermine (hydrochloride)

N1-Acetylspermine is a monoacetylated derivative of spermine (Cay-18041), an endogenous polyamine synthesized from spermidine (Cay-14918), that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. N1-Acetylspermine has been used to study the uptake of the anticancer polyamine analog bleomycin-A5 by the human carnitine transporter SLC22A16.Formal Name: N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-acetamide, trihydrochloride. CAS Number: 77928-70-2. Molecular Formula: C12H28N4O . 3HCl. Formula Weight: 353.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: :, :, :, Water: 50 mg/ml. SMILES: CC(NCCCNCCCCNCCCN)=O.Cl.Cl.Cl. InChi Code: InChI=1S/C12H28N4O.3ClH/c1-12(17)16-11-5-10-15-8-3-2-7-14-9-4-6-13,,,/h14-15H,2-11,13H2,1H3,(H,16,17),3*1H. InChi Key: QQSPUTBJDXPUCR-UHFFFAOYSA-N.