N,N'-Diacetyl-L-cystine

N,N'-Diacetyl-L-cystine (DiNAC) is a disulfide dimer of N-acetylcysteine with immunomodulatory properties. Its intact disulfide bridge has been shown to be important for its ability to modify contact sensitivity/delayed hypersensitivity reactions in mice. At 3 µM/kg/day, DiNAC also demonstrates anti-atherosclerotic effects, improving endothelial function in Watanabe heritable hyperlipidemic rabbits.Formal Name: (2R,2'R)-3,3'-disulfanediylbis(2-acetamidopropanoic acid). CAS Number: 5545-17-5. Synonyms: N,N'-Diacetylcystine, DiNAC, NSC 203780. Molecular Formula: C10H16N2O6S2. Formula Weight: 324.4. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: OC([C@@H](NC(C)=O)CSSC[C@H](NC(C)=O)C(O)=O)=O. InChi Code: InChI=1S/C10H16N2O6S2/c1-5(13)11-7(9(15)16)3-19-20-4-8(10(17)18)12-6(2)14/h7-8H,3-4H2,1-2H3,(H,11,13)(H,12,14)(H,15,16)(H,17,18)/t7-,8-/m0/s1. InChi Key: YTPQSLLEROSACP-YUMQZZPRSA-N.