N-acetyl-L-Alanine

N-acetyl-L-Alanine is an endogenous metabolite. It decreases IFN-gamma production induced by radiation-killed M. tuberculosis in natural killer (NK) cells isolated from patients with latent M. tuberculosis infection when used at a concentration of 3 µM. N-acetyl-L-Alanine (3 µM) also decreases ATP production and glycolytic flux in naïve or radiation-killed M. tuberculosis-exposed isolated human NK cells. Brain levels of N-acetyl-L-alanine are decreased in a rat model of diabetic neuropathic pain induced by streptozotocin (STZ, Cay-13104). Increased urine levels of N-acetyl-L-alanine are associated with mutations in the gene encoding aminoacylase-1 (ACY1), an enzyme involved in the hydrolysis of N-acetylated proteins.CAS Number: 97-69-8. Synonyms: N-Acetylalanine, NSC 186892. Molecular Formula: C5H9NO3. Formula Weight: 131.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: Soluble. SMILES: OC([C@@H](NC(C)=O)C)=O. InChi Code: InChI=1S/C5H9NO3/c1-3(5(8)9)6-4(2)7/h3H,1-2H3,(H,6,7)(H,8,9)/t3-/m0/s1. InChi Key: KTHDTJVBEPMMGL-VKHMYHEASA-N.