N-acetyl-D-Galactosamine

N-acetyl-D-Galactosamine (GalNAc) is an amino sugar derivative of galactose and a component of O-GalNAc glycans. It is transferred from UDP-GalNAc to the hydroxy group of protein serine or threonine residues by polypeptide GalNAc transferase, forming the Tn antigen, during the first step of mucin-type O-glycosylation. GalNAc has been used as a targeting moiety for liver-targeted delivery of oligonucleotides.Formal Name: 2-(acetylamino)-2-deoxy-D-galactose. CAS Number: 1811-31-0. Synonyms: N-Acetylgalactosamine, GalNAc. Molecular Formula: C8H15NO6. Formula Weight: 221.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: O=C[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@H](O)CO. InChi Code: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8-/m0/s1. InChi Key: MBLBDJOUHNCFQT-OSMVPFSASA-N.