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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T39716-5mg | 5 mg |
7 - 10 business days* |
951.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Mutant IDH1-IN-6 is an orally active compound that effectively inhibits mutant... more
Product information "Mutant IDH1-IN-6"
Description: Mutant IDH1-IN-6 is an orally active compound that effectively inhibits mutant isocitrate dehydrogenase (IDH) enzymes. It demonstrates potency and selectivity, with IC50 values of 6.27, 3.71, 36.9, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutants, respectively. Notably, Mutant IDH1-IN-6 exhibits lower activity in inhibiting wild-type IDH enzymes. Target: Others. Smiles: CCN1C(=O)OCc2cnc(N[C@@H](C)c3ccc(cc3)[C@H](CC3CC3)N3CCN(CC3)C(=O)C=C)nc12. References: Renato Alejandro BAUER, et al. 7-phenylethylamino-4h-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant idh1 and idh2 inhibitors. WO2018111707A1.
| Keywords: | Mutant IDH1-IN-6 |
| Supplier: | TargetMol |
| Supplier-Nr: | T39716 |
Properties
| Application: | Targets isocitrate dehydrogenase [EC:1.1.1.42] (IDH1, IDH2, icd) |
| MW: | 504.635 D |
| Formula: | C28H36N6O3 |
Database Information
| CAS : | 2230263-60-0| Matching products |
| KEGG ID : | K00031 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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