MT-802
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802... more
Product information "MT-802"
Description: MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL). Target: PROTACs, BTK. Smiles: NC1=C2C(=NN(C2=NC=N1)C3CCN(CCOCCOCC(NC=4C=C5C(=CC4)C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=O)CC3)C7=CC=C(OC8=CC=CC=C8)C=C7. References: Buhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3,57(26):3564-3575.
| Supplier: | TargetMol |
| Supplier-Nr: | T16157 |
Properties
| Application: | BTK degradation driving PROTAC |
| MW: | 787.82 D |
| Formula: | C41H41N9O8 |
Database Information
| CAS : | 2231744-29-7| Matching products |
| KEGG ID : | K07370 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H311, H331 |
| P Phrases: | P261, P264, P270, P271, P280, P311, P312, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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