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Description: MSAB is a selective inhibitor of Wnt/beta-catenin signaling. MSAB binds to beta-catenin, promoting its degradation, and specifically downregulates Wnt/beta-catenin target genes. Target: Wnt/beta-catenin. Smiles: COC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1. References: Hwang SY, et, al. Direct Targeting of beta-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/beta-Catenin Signaling. Cell Rep. 2016 Jun 28,16(1):28-36.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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