MRK-560
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: MRK-560 is an effective and brain-penetrant inhibitor of gamma-secretase. Target:... more
Product information "MRK-560"
Description: MRK-560 is an effective and brain-penetrant inhibitor of gamma-secretase. Target: Gamma-secretase. Smiles: Fc1ccc(F)c(c1)[C@]1(CC[C@@H](CC1)NS(=O)(=O)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1. References: Best JD, et al. The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse. J Pharmacol Exp Ther. 2007 Feb,320(2):552-8.
| Supplier: | TargetMol |
| Supplier-Nr: | T16133 |
Properties
| MW: | 517.92 D |
| Formula: | C19H17ClF5NO4S2 |
Database Information
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319 |
| P Phrases: | P264, P280, P302+352, P305+351+338, P321, P332+313, P337+313, P362+364 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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