Monomethyl auristatin E
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division... more
Product information "Monomethyl auristatin E"
Description: Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity. Target: Microtubule Associated, Apoptosis, ADC Cytotoxin. Smiles: CC[C@H](C)C([C@@H](CC(=O)N1CCC[C@H]1C(OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)[C@@H](C(C)C)C(=O)NC(=O)[C@@H](NC)C(C)C. References: Francisco JA, et al. Blood. 2003, 102(4), 1458-1465.
| Keywords: | Vedotin, MMAE |
| Supplier: | TargetMol |
| Supplier-Nr: | T6897 |
Properties
| Application: | Targets tubulin beta (TUBB) |
| MW: | 717.98 D |
| Formula: | C39H67N5O7 |
Database Information
| CAS : | 474645-27-7| Matching products |
| KEGG ID : | K07375 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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