Monocrotaline
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Monocrotaline (Crotaline) is a pyrrolizidine alkaloid and a toxic plant constituent... more
Product information "Monocrotaline"
Description: Monocrotaline (Crotaline) is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes is noted after oral magnesium treatment. Target: TGF-beta/Smad. Smiles: C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)C23. References: Gomez-Arroyo JG, et al. The monocrotaline model of pulmonary hypertension in perspective. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 15,302(4):L363-9.
| Keywords: | Crotaline |
| Supplier: | TargetMol |
| Supplier-Nr: | T2803 |
Properties
| Application: | Pulmonary hypertension inducer |
| MW: | 325.36 D |
| Formula: | C16H23NO6 |
Database Information
| CAS : | 315-22-0| Matching products |
| KEGG ID : | K17689 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H351 |
| P Phrases: | P201, P202, P264, P270, P280, P301+310, P308+313, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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