Momelotinib

Item number	Size	Delivery time	Price
TGM-T1849-1mg	1 mg	7 - 10 business days*	33.00€
TGM-T1849-2mg	2 mg	7 - 10 business days*	45.00€
TGM-T1849-5mg	5 mg	7 - 10 business days*	74.00€
TGM-T1849-1mL	1 ml	7 - 10 business days*	81.00€
TGM-T1849-10mg	10 mg	7 - 10 business days*	97.00€
TGM-T1849-25mg	25 mg	7 - 10 business days*	167.00€
TGM-T1849-50mg	50 mg	7 - 10 business days*	271.00€
TGM-T1849-100mg	100 mg	7 - 10 business days*	427.00€
TGM-T1849-200mg	200 mg	7 - 10 business days*	655.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Description: Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus... more

Close menu

Product information "Momelotinib"

Description: Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells. Target: Autophagy, Apoptosis, JAK. Smiles: O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1. References: Pardanani A, et al. Leukemia, 2009, 23(8), 1441-1445.

Keywords:	CYT387, LM-1149, CYT11387
Supplier:	TargetMol
Supplier-Nr:	T1849

Properties

Application:	Targets Janus kinase 1 [EC:2.7.10.2] (JAK1)
MW:	414.46 D
Formula:	C23H22N6O2
Format:	32160405

Database Information

CAS :	1056634-68-4\| Matching products
KEGG ID :	K04447 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "Momelotinib"

Write a review