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Description: ML417 is a selective and brain-penetrant agonist of D3 dopamine (EC50: 38 nM). Target: Dopamine Receptor, Arrestin. Smiles: COc1ccc(OCCN2CCN(CC2)C(=O)c2cc3ccccc3[nH]2)cc1. References: Moritz AE, et al. Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist. J Med Chem. 2020,63(10):5526-5567.
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