ML385
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: ML385 is an NRF2 inhibitor (IC50=1.9 µM) with novelty and specificity. ML385 has... more
Product information "ML385"
Description: ML385 is an NRF2 inhibitor (IC50=1.9 µM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity. Target: Others, Ferroptosis, Nrf2. Smiles: Cc1sc(NC(=O)Cc2ccc3OCOc3c2)nc1-c1ccc2N(CCc2c1)C(=O)c1ccccc1C. References: Singh A, et al. Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors. ACS Chem Biol. 2016 Nov 18,11(11):3214-3225.
| Supplier: | TargetMol |
| Supplier-Nr: | T4360 |
Properties
| Application: | NRF2 inhibitor |
| MW: | 511.59 D |
| Formula: | C29H25N3O4S |
Database Information
| CAS : | 846557-71-9| Matching products |
| KEGG ID : | K10456 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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