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Description: ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3. Target: ALK, TGF-beta/Smad. Smiles: COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12. References: Engers DW, et al. Bioorg Med Chem Lett. 2013, 23(11), 3248-3252.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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