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Description: ML228 is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 µM. ML228 potently activates HIF in vitro as well as its downstream target VEGF. Target: HIF. Smiles: C(Nc1nc(nnc1-c1ccccc1)-c1ccccn1)c1ccc(cc1)-c1ccccc1. References: Theriault JR, et al. Discovery of a Small Molecule Activator of the Hypoxia Inducible Factor Pathway. Probe Reports from the NIH Molecular Libraries Program.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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