ML 209

Item number	Size	Delivery time	Price
TGM-T37587-1mg	1 mg	7 - 10 business days*	93.00€
TGM-T37587-5mg	5 mg	7 - 10 business days*	220.00€
TGM-T37587-10mg	10 mg	7 - 10 business days*	287.00€
TGM-T37587-25mg	25 mg	7 - 10 business days*	471.00€
TGM-T37587-50mg	50 mg	7 - 10 business days*	685.00€
TGM-T37587-100mg	100 mg	7 - 10 business days*	942.00€
TGM-T37587-500mg	500 mg	7 - 10 business days*	1,882.00€

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Description: ML-209 is an antagonist of retinoic acid receptor-related orphan receptor gammat... more

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Product information "ML 209"

Description: ML-209 is an antagonist of retinoic acid receptor-related orphan receptor gammat (RORgammat, IC50= 1.1 µM in a reporter assay).1It inhibits RORgammat-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM). ML-209 inhibits RORgammat-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells. Target: ROR. Smiles: C(CC(=O)N1C[C@@H](C)C[C@@H](C)C1)(C2=C(OC)C=C(OC)C=C2O)C=3C=C4C(=CC3)OCO4. References: Huh, J.R., Englund, E.E., Wang, H., et al.Identification of potent and selective diphenylpropanamide RORgamma inhibitorsACS Med. Chem. Lett.4(1)79-84(2013)

Supplier:	TargetMol
Supplier-Nr:	T37587

Properties

Application:	RORgammat antagonist
MW:	441.52 D
Formula:	C25H31NO6

Database Information

CAS :	1334526-14-5\| Matching products
KEGG ID :	K08534 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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