MKC8866

Item number	Size	Manual	Delivery time	Price
TGM-T15594-1mg	1 mg	-	7 - 10 business days*	78.00€
TGM-T15594-5mg	5 mg	-	7 - 10 business days*	192.00€
TGM-T15594-1mL	1 ml	-	7 - 10 business days*	208.00€
TGM-T15594-10mg	10 mg	-	7 - 10 business days*	313.00€
TGM-T15594-25mg	25 mg	-	7 - 10 business days*	527.00€
TGM-T15594-50mg	50 mg	-	7 - 10 business days*	763.00€
TGM-T15594-100mg	100 mg	-	7 - 10 business days*	1,069.00€
TGM-T15594-500mg	500 mg	-	7 - 10 business days*	2,139.00€

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Description: MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 µM in human vitro). MKC8866... more

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Product information "MKC8866"

Description: MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 µM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth. Target: IRE1. Smiles: COc1cc2c(C)c(CC(=O)N3CCOCC3)c(=O)oc2c(C=O)c1O. References: Sheng X, et al. IRE1alpha-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nat Commun. 2019 Jan 24,10(1):323.

Supplier:	TargetMol
Supplier-Nr:	T15594

Properties

Application:	IRE1alpha RNase activity inhibitor
MW:	361.35 D
Formula:	C18H19NO7

Database Information

CAS :	1338934-59-0\| Matching products
KEGG ID :	K08852 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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