MitoP

MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB (Cay-17116). MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP. Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.Formal Name: [(3-hydroxyphenyl)methyl]triphenyl-phosphonium, monobromide. CAS Number: 74597-01-6. Synonyms: MitoPhenol. Molecular Formula: C25H22OP . Br. Formula Weight: 449.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 12 mg/ml. lambdamax: 276 nm. SMILES: OC1=CC=CC(C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=C1.[Br-]. InChi Code: InChI=1S/C25H21OP.BrH/c26-22-12-10-11-21(19-22)20-27(23-13-4-1-5-14-23,24-15-6-2-7-16-24)25-17-8-3-9-18-25,/h1-19H,20H2,1H. InChi Key: SVALDZORJHFRCU-UHFFFAOYSA-N.