Mirdametinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective,... more
Product information "Mirdametinib"
Description: Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis. Target: Autophagy, MEK, Apoptosis. Smiles: OC[C@@H](O)CONC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F. References: Ciuffreda L, et al. Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations. Neoplasia. 2009 Aug,11(8):720-31.
| Keywords: | PD0325901, PD325901 |
| Supplier: | TargetMol |
| Supplier-Nr: | T6189 |
Properties
| Application: | Targets mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] (MAP2K1, MEK1) |
| MW: | 482.19 D |
| Formula: | C16H14F3IN2O4 |
Database Information
| CAS : | 391210-10-9| Matching products |
| KEGG ID : | K04368 | Matching products |
| Protein Atlas Nr. : | Phosphorylation (other) |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H413 |
| P Phrases: | P264, P270, P273, P321, P330, P301+P310, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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