Mildronate dihydrate

Mildronate dihydrate
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CDX-M0558-M010 10 mg - -

3 - 9 business days*

37.00€
CDX-M0558-M025 25 mg - -

3 - 9 business days*

85.00€
 
White to off-white powder. Soluble in water (20mg/ml) or ethanol (20mg/ml). Chemical. CAS:... more
Product information "Mildronate dihydrate"
White to off-white powder. Soluble in water (20mg/ml) or ethanol (20mg/ml). Chemical. CAS: 86426-17-7. Formula: C6H14N2O2 . 2H2O. MW: 182.22. Mildronate is a structural analog of gamma-butyrobetaine (gammaBB), an intermediate in the biosynthesis of carnitine and a modulator of energy metabolism. It blocks carnitine synthesis by inhibiting gammaBB hydroxylase (BBOX) and, less potently, carnitine acetyltransferase (CrAT). Through these actions, mildronate reduces the levels of free carnitine and long chain acyl carnitine. This leads to suppressed fatty acid metabolism and mitochondrial uncoupling during oxidative conditions, resulting in cardioprotective, antidiabetic and neuroprotective effects. Mildronate also improves cognition and reduces amyloid-beta pathology in a mouse model of Alzheimer's disease.
Keywords: Meldonium, MET 88, Quaterin, THP
Supplier: Chemodex
Supplier-Nr: M0558

Properties

MW: 182,22 D
Formula: C6H14N2O2 . 2H2O
Purity: > 98% (HPLC)
Format: Solid

Database Information

CAS : 86426-17-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315-H319-H335
P Phrases: P261-P305+P351+P338
Caution
Our products are for laboratory research use only: Not for administration to humans!
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