MI-2-2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T28036-1mg	1 mg				7 - 10 business days*		58.00€
TGM-T28036-5mg	5 mg				7 - 10 business days*		-

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Description: MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL... more

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Product information "MI-2-2"

Description: MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM. Target: Histone Methyltransferase. Smiles: C(C(F)(F)F)C1=CC2=C(N=CN=C2S1)N3CCN(CC3)C=4SC(C)(C)CN4. References: Shi A, et al. Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia. Blood. 2012,120(23):4461-4469.

Keywords:	MI22, MI 2 2
Supplier:	TargetMol
Supplier-Nr:	T28036

Properties

Application:	Menin-MLL1 protein-protein interaction inhibitor
MW:	415.5 D
Formula:	C17H20F3N5S2

Database Information

CAS :	1454920-20-7\| Matching products
KEGG ID :	K14970 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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