MHY1485

MHY1485 is a cell-permeable activator of mTOR that has been shown to increase levels of cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation in rat liver Ac2F cells. It can induce cellular LC3-II accumulation in Ac2F cells and has been shown to inhibit autophagy by suppressing the fusion between autophagosomes and lysosomes.Formal Name: 4,6-di-4-morpholinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amine. CAS Number: 326914-06-1. Molecular Formula: C17H21N7O4. Formula Weight: 387.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 0.5 mg/ml. lambdamax: 233, 349 nm. SMILES: O=[N+](C(C=C1)=CC=C1NC2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)[O-]. InChi Code: InChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H,5-12H2,(H,18,19,20,21). InChi Key: MSSXBKQZZINCRI-UHFFFAOYSA-N.