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Description: Methysergide is used for prophylaxis of migraine headaches/cluster headaches but is no longer recommended due to retropulmonary/retroperitoneal fibrosis. It may also be used in the treatment of serotonin syndrome. It is also used in carcinoid syndrome to treat severe diarrhea. Target: Others. Smiles: C(=C\C(O)=O)\C(O)=O.CN1C2=C3C(C=4[C@@](CC3=C1)(N(C)C[C@H](C(N[C@@H](CC)CO)=O)C4)[H])=CC=C2. References: Valic M, Pecotic R, Pavlinac Dodig I, Valic Z, Stipica I, Dogas Z. Intermittent hypercapnia-induced phrenic long-term depression is revealed after serotonin receptor blockade with methysergide in anaesthetized rats. Exp Physiol. 2016 Feb 1,101(2):319-31. doi: 10.1113/EP085161. Epub 2015 Dec 20. PubMed PMID: 26621042.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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