Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay13118-1 | 1 g | - |
6 - 10 business days* |
32.00€
|
|||
Cay13118-5 | 5 g | - |
6 - 10 business days* |
47.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.)... more
Product information "Metformin (hydrochloride)"
Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day. It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD). Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53-\- human colon cancer mouse xenograft model, but has no effect on HCT116 p53-\- tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I. Formulations containing metformin have been used in the treatment of type 2 diabetes.Formal Name: N,N-dimethyl-imidodicarbonimidic diamide, monohydrochloride. CAS Number: 1115-70-4. Synonyms: 1,1-Dimethylbiguanide hydrochloride. Molecular Formula: C4H11N5 . HCl. Formula Weight: 165.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 237 nm. SMILES: CN(C)C(NC(N)=N)=N.Cl. InChi Code: InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6,/h1-2H3,(H5,5,6,7,8),1H. InChi Key: OETHQSJEHLVLGH-UHFFFAOYSA-N.
Keywords: | 1,1-Dimethylbiguanide hydrochloride, N,N-dimethyl-imidodicarbonimidic diamide, monohydrochloride |
Supplier: | Cayman Chemical |
Supplier-Nr: | 13118 |
Properties
Application: | AMPK activator |
MW: | 165.6 D |
Formula: | C4H11N5 . HCl |
Purity: | >98% |
Format: | Crystalline Solid |
Database Information
CAS : | 1115-70-4| Matching products |
KEGG ID : | K07198 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H302, H319 |
P Phrases: | P264, P270, P280, P301+310, P305+351+338, P330, P337+313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed