Metacetamol

Metacetamol is a derivative of acetaminophen (Cay-10024). Unlike acetaminophen, metacetamol is not cytotoxic to isolated mouse hepatocytes (LC50 = >10 mM). However, it does induce necrosis and depletion of glutathione (GSH) in isolated human hepatocytes when used at a concentration of 10 mM. Metacetamol (900 mg/kg) does not induce hepatic necrosis in mice.Formal Name: N-(3-hydroxyphenyl)-acetamide. CAS Number: 621-42-1. Synonyms: 3'-Hydroxyacetanilide, AMAP, N-acetyl-m-Aminophenol, N-acetyl-meta-Aminophenol, NSC 3990. Molecular Formula: C8H9NO2. Formula Weight: 151.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml, Ethanol: 5 mg/ml. lambdamax: 246 nm. SMILES: O=C(C)NC1=CC(O)=CC=C1. InChi Code: InChI=1S/C8H9NO2/c1-6(10)9-7-3-2-4-8(11)5-7/h2-5,11H,1H3,(H,9,10). InChi Key: QLNWXBAGRTUKKI-UHFFFAOYSA-N.