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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T11972-25mg | 25 mg | - |
7 - 10 business days* |
1,491.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo... more
Product information "Mcl-1 inhibitor 3"
Description: Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM, IC50=19 nM in an OPM-2 cell viability assay). Target: BCL. Smiles: [H][C@@]12CC[C@@]1([H])[C@@H](OCCN1CC(F)(F)C1)\C=C/CCN(C)C(=O)C[C@](O)(C(=O)NS(=O)(=O)N(C)C)c1ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C2)c3c1 , c:18, . References: Rescourio G, Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an alpha-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.J Med Chem. 2019 Nov 27,62(22):10258-10271.
| Supplier: | TargetMol |
| Supplier-Nr: | T11972 |
Properties
| Application: | Mcl-1 inhibitor |
| MW: | 820.39 D |
| Formula: | C40H52ClF2N5O7S |
Database Information
| CAS : | 2376774-73-9| Matching products |
| KEGG ID : | K02539 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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