MBP146-78

Item number	Size	Manual	SDS	Delivery time	Price
SYN-1227-M001	1 mg	-	-	3 - 9 business days*	108.00€
SYN-1227-M005	5 mg	-	-	3 - 9 business days*	169.00€
SYN-1227-M010	10 mg	-	-	3 - 9 business days*	231.00€
SYN-1227-M050	50 mg	-	-	3 - 9 business days*	847.00€
SYN-1227-M100	100 mg	-	-	3 - 9 business days*	-

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MBP146-78 inhibits the growth of Eimeria spp. both in vitro and in vivo. The molecular target of... more

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Product information "MBP146-78"

MBP146-78 inhibits the growth of Eimeria spp. both in vitro and in vivo. The molecular target of MBP146-78 was identified as cGMP-dependent protein kinase (PKG) using a tritiated analogue to purify a approximately 120-kDa protein from lysates of Eimeria tenella. This represents the first example of a protozoal PKG. MBP146-78 is a potent inhibitor of both soluble and membrane-associated isoforms of native PKG, as well as recombinant enzyme, with an IC50 of <1nm.

Keywords:	4-[2-(4-Fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl] pyridine
Supplier:	SYNkinase
Supplier-Nr:	1227

Properties

Application:	Eimeria spp. cGMP-dependent protein kinase (PKG) inhibitor
MW:	335.4 D
Formula:	C21H22FN3
Purity:	>95% (HPLC)
Format:	Solid

Database Information

CAS :

188343-77-3| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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View product citations for antibody 1227 on CiteAb

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