Manumycin A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T16011-1mg	1 mg		-		7 - 10 business days*		272.00€
TGM-T16011-5mg	5 mg		-		7 - 10 business days*		967.00€

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Description: Manumycin A is an antibiotic with anticancer activity and is a mammalian thioredoxin... more

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Product information "Manumycin A"

Description: Manumycin A is an antibiotic with anticancer activity and is a mammalian thioredoxin reductase-1 (TrxR-1) inhibitor.Manumycin A inhibits the production of IL-1beta, IL-6, and IL-8 in TNF alpha-stimulated THP-1 cells and peripheral blood mononuclear cells in a dose-dependent manner, inducing apoptosis. Target: TNF, Apoptosis. Smiles: [H][C@]12O[C@@]1([H])[C@](O)(\C=C\C=C\C=C\C(=O)NC1=C(O)CCC1=O)C=C(NC(=O)C(\C)=C\C(\C)=C\[C@H](C)CCCC)C2=O. References: Hara M, et al. Identification of Ras farnesyltransferase inhibitors by microbial screening. Proc Natl Acad Sci U S A. 1993 Mar 15,90(6):2281-5.

Supplier:	TargetMol
Supplier-Nr:	T16011

Properties

Application:	Rasfarnesyltransferase inhibitor
MW:	550.64 D
Formula:	C31H38N2O7

Database Information

CAS :	52665-74-4\| Matching products
KEGG ID :	K05954 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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