LysoFP-NO2

LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 µM.Formal Name: 2-[2-(4-morpholinyl)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione. CAS Number: 69408-75-9. Molecular Formula: C18H17N3O5. Formula Weight: 355.3. Purity: >98%. Emission: 528 nm. Excitation: 440 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 30 mg/ml. lambdamax: 219, 275, 332 nm. SMILES: O=C1C2=C3C(C(N1CCN4CCOCC4)=O)=CC=CC3=CC([N+]([O-])=O)=C2. InChi Code: InChI=1S/C18H17N3O5/c22-17-14-3-1-2-12-10-13(21(24)25)11-15(16(12)14)18(23)20(17)5-4-19-6-8-26-9-7-19/h1-3,10-11H,4-9H2. InChi Key: MQBIIGAYEJQXCC-UHFFFAOYSA-N.