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Description: lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM). Target: Dopamine Receptor, 5-HT Receptor. Smiles: Cc1ccc(cc1)S(O)(=O)=O.CN1CCN2C3CCN(CCCC(=O)c4ccc(F)cc4)CC3c3cccc1c23. References: Vyas P, et al. An evaluation of lumateperone tosylate for the treatment of schizophrenia. Expert Opin Pharmacother. 2020 Feb,21(2):139-145.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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