Lovastatin Hydroxy Acid (sodium salt)

Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name: 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, butanoic acid, monosodium salt. CAS Number: 75225-50-2. Molecular Formula: C24H37O6 . Na. Formula Weight: 444.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml. lambdamax: 231, 238, 246 nm. SMILES: C[C@H]1C=CC2=C[C@H](C)C[C@H](OC([C@@H](C)CC)=O)[C@]2([H])[C@H]1CC[C@@H](O)C[C@@H](O)CC([O-])=O.[Na+]. InChi Code: InChI=1S/C24H38O6.Na/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28,/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28),/q,+1/p-1/t14-,15-,16-,18+,19+,20-,21-,23-,/m0./s1. InChi Key: LXZBFUBRYYVRQJ-AXHZAXLDSA-M.