Losartan Carboxylic Acid

Item number	Size	Manual	Delivery time	Price
TGM-T3461-5mg	5 mg	-	7 - 10 business days*	43.00€
TGM-T3461-1mL	1 ml	-	7 - 10 business days*	48.00€
TGM-T3461-10mg	10 mg	-	7 - 10 business days*	71.00€
TGM-T3461-25mg	25 mg	-	7 - 10 business days*	144.00€
TGM-T3461-50mg	50 mg	-	7 - 10 business days*	257.00€
TGM-T3461-100mg	100 mg	-	7 - 10 business days*	384.00€
TGM-T3461-200mg	200 mg	-	7 - 10 business days*	564.00€

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Description: Losartan Carboxylic Acid (E-3174), a potent AT1 antagonist (Kis: 0.57 nM, rat, 0.67... more

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Product information "Losartan Carboxylic Acid"

Description: Losartan Carboxylic Acid (E-3174), a potent AT1 antagonist (Kis: 0.57 nM, rat, 0.67 nM, human), produces a depressor response and vasodilatation. As a metabolite of losartan, it is more potent than losartan in blocking angiotensin II-induced responses in vascular smooth muscle cells. Target: RAAS. Smiles: C(N1C(CCCC)=NC(Cl)=C1C(O)=O)C2=CC=C(C=C2)C3=C(C=CC=C3)C=4NN=NN4. References: Choi JS, Choi JS, Choi DH. Effects of licochalcon A on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats. Pharmazie. 2013 Nov,68(11):882-8.

Keywords:	EXP-3174, E-3174
Supplier:	TargetMol
Supplier-Nr:	T3461

Properties

Application:	AGTR1 antagonist
MW:	436.89 D
Formula:	C22H21ClN6O2

Database Information

CAS :	124750-92-1\| Matching products
KEGG ID :	K04166 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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