LM10
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 µM... more
Product information "LM10"
Description: Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 µM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable. Target: Others. Smiles: Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1. References: Pilotte L,etal.Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.Proc Natl Acad Sci U S A. 2012 Feb 14,109(7):2497-502.
| Supplier: | TargetMol |
| Supplier-Nr: | T4410 |
Properties
| Application: | TDO inhibitor |
| MW: | 229.21 D |
| Formula: | C11H8FN5 |
Database Information
| CAS : | 1316695-35-8| Matching products |
| KEGG ID : | K00453 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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