Lenalidomide
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Lenalidomide (CC-5013) is an immunomodulator with oral activity. Lenalidomide is a... more
Product information "Lenalidomide"
Description: Lenalidomide (CC-5013) is an immunomodulator with oral activity. Lenalidomide is a ligand for the ubiquitin E3 ligase cereblon (CRBN), which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase, and is commonly used in the synthesis of PROTAC products. Target: Ligand for E3 Ligase, Apoptosis, TNF, Molecular Glues. Smiles: NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1. References: Kim K, et al. Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cells. Oncol Lett. 2013 Feb,5(2):588-592.
| Keywords: | CC-5013 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1642 |
Properties
| Application: | Targets tumor necrosis factor superfamily, member 2 (TNF, TNFA) |
| MW: | 259.26 D |
| Formula: | C13H13N3O3 |
Database Information
| CAS : | 191732-72-6| Matching products |
| KEGG ID : | K03156 | Matching products |
| Protein Atlas Nr. : | Ligands |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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