LDN193189
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting... more
Product information "LDN193189"
Description: LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for ALK1/2/3/6). Target: ALK, TGF-beta/Smad. Smiles: C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12. References: Yu PB, et al. BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med. 2008 Dec,14(12):1363-9.
| Keywords: | DM-3189, LDN 193189, LDN-193189 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1935 |
Properties
| Application: | BMP type I receptor inhibitor |
| MW: | 406.48 D |
| Formula: | C25H22N6 |
Database Information
| CAS : | 1062368-24-4| Matching products |
| KEGG ID : | K13594 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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